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KRAS Monoclonal Antibody [PAT2F8AT] (CPAB0633)

SKU:
CPAB0633
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2F8AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

KRAS Monoclonal Antibody [PAT2F8AT] (CPAB0633)

The KRAS Polyclonal Antibody (CPAB0633) is a powerful tool for researchers studying the KRAS (Kirsten rat sarcoma viral oncogene homolog) protein, a key player in cell signaling pathways involved in cell growth and division. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the KRAS protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential component for studies in cancer biology and drug development.

KRAS is a commonly mutated gene in various cancers, including colorectal, lung, and pancreatic cancer. Understanding the function and dysregulation of KRAS is essential for developing targeted therapies that can effectively treat these aggressive forms of cancer. The KRAS Polyclonal Antibody allows researchers to delve deeper into the mechanisms involving KRAS, providing valuable insights that can lead to the development of novel cancer treatments.

Product Name:KRAS Antibody
Product Sku:CPAB0633
Size:5μg
Host Species:Mouse
Immunogen:Anti-human KRAS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human KRAS protein 1-186 amino acids purified from Ecoli.
Clone:PAT2F8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:KRAS antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:Kirsten Rat Sarcoma Viral Oncogene, Isoform 2A (KRAS-2A) belongs to the small GTPase superfamily. The KRAS-2A protein is involved in a variety of malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Ras family members impact cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system under normal conditions. Oncogenic Ras can deregulate processes which control both cell proliferation and apoptosis.
Synonyms:GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras, KRAS, KRAS2, RASK2, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, NS, NS3, Kirsten rat sarcoma viral oncogene homolog.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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