KPNA6 Rabbit Polyclonal Antibody (CAB7363)
- SKU:
- CAB7363
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | KPNA6 Rabbit Polyclonal Antibody |
SKU: | CAB7363 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-536 of human KPNA6 (NP_036448.1). |
Sequence: | SYLS DGPN EKIQ AVID SGVC RRLV ELLM HNDY KVAS PALR AVGN IVTG DDIQ TQVI LNCS ALPC LLHL LSSP KESI RKEA CWTI SNIT AGNR AQIQ AVID ANIF PVLI EILQ KAEF RTRK EAAW AITN ATSG GTPE QIRY LVSL GCIK PLCD LLTV MDSK IVQV ALNG LENI LRLG EQEG KRSG SGVN PYCG LIEE AYGL DKIE FLQS HENQ EIYQ KAFD LIEH YFGV EDDD SSLA PQVD ETQQ QFIF QQPE APME GFQL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | IPOA7; KPNA6 |
Positive Sample: | HeLa,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, nucleoplasm, nucleus |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
Purification Method: | Affinity purification |
Gene ID: | 23633 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |