The KPNA3 Polyclonal Antibody (CAB16907) is a valuable tool for researchers studying KPNA3, a key protein involved in nucleocytoplasmic transport. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in techniques such as Western blotting.KPNA3, also known as importin alpha-4, plays a critical role in transporting proteins into the nucleus, a crucial process for DNA replication, transcription, and other essential cellular functions. Dysregulation of KPNA3 has been linked to various diseases, including cancer, making it a promising target for further research.
With its ability to specifically bind to KPNA3, this polyclonal antibody enables researchers to detect and analyze the protein in different cell types, providing insights into its function and potential therapeutic applications. Whether investigating nucleocytoplasmic transport mechanisms or exploring KPNA3's role in disease progression, this antibody is a valuable asset for immunology, oncology, and cell biology studies.
Product Name:
KPNA3 Rabbit Polyclonal Antibody
SKU:
CAB16907
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human KPNA3 (NP_002258.2).
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
Purification Method:
Affinity purification
Gene ID:
3839
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells using KPNA3 Rabbit pAb (CAB16907) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
