The KPNA3 Polyclonal Antibody (CAB8347) is a valuable tool for researchers studying the role of KPNA3, a key player in nucleocytoplasmic transport processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications.KPNA3, also known as importin alpha-4, is essential for the transport of proteins into the nucleus, playing a critical role in gene regulation and cellular function. Aberrant expression of KPNA3 has been linked to various diseases, including cancer and viral infections, making it a target of interest for therapeutic development.
By binding specifically to KPNA3 protein, this antibody enables researchers to detect and analyze its expression in different cell types, offering insights into its function and potential as a therapeutic target. With its strong reactivity and validation for Western blotting, the KPNA3 Polyclonal Antibody is a valuable tool for studies in molecular biology, cancer research, and infectious diseases.
Product Name:
KPNA3 Rabbit Polyclonal Antibody
SKU:
CAB8347
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human KPNA3 (NP_002258.2).
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
Purification Method:
Affinity purification
Gene ID:
3839
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using KPNA3 Rabbit pAb (CAB8347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
