The ZMYND8 Polyclonal Antibody (CAB8737) is a valuable tool for researchers studying the ZMYND8 protein, which plays a key role in chromatin remodeling and transcriptional regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding specifically to the ZMYND8 protein, this antibody allows for the detection and analysis of ZMYND8 expression in various cell types, making it an essential tool for studies in epigenetics, cancer research, and gene transcription.
ZMYND8, also known as Zinc finger MYND-containing protein 8, has been implicated in various cellular processes, including cell differentiation, proliferation, and DNA damage response. Understanding the function of ZMYND8 is crucial for uncovering its role in disease development, particularly in cancer and neurodegenerative disorders. By targeting ZMYND8 with this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic targets for intervention.
Product Name:
[KO Validated] ZMYND8 Rabbit Polyclonal Antibody
SKU:
CAB8737
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 959-1188 of human ZMYND8 (NP_898868.1).
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
23613
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using ZMYND8 antibody (CAB8737) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
