The YBX1 Polyclonal Antibody (CAB7704) is a valuable tool for researchers studying the YBX1 protein, a multifunctional protein involved in RNA processing and DNA repair processes. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and has been validated for its high reactivity with human samples.YBX1, also known as Y-box binding protein 1, plays a critical role in regulating gene expression, DNA repair, and cell proliferation. It is implicated in a variety of biological processes, making it a key target for research in fields such as cancer biology, developmental biology, and molecular biology.
The YBX1 Polyclonal Antibody enables precise detection and analysis of the YBX1 protein in various cell types, making it an essential tool for studies aiming to understand the molecular mechanisms underlying these processes.By using the YBX1 Polyclonal Antibody in their research, scientists can gain valuable insights into the role of YBX1 in normal cellular functions and disease processes. This antibody offers a reliable and specific method for studying YBX1 expression, localization, and function, ultimately contributing to the advancement of knowledge in the fields of molecular biology and biomedicine.
This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.
Purification Method:
Affinity purification
Gene ID:
4904
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using YB-1/YBX1 Rabbit pAb (CAB7704) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
