The TOMM34 Polyclonal Antibody (CAB19960) is a valuable tool for researchers studying TOMM34, a protein involved in mitochondrial protein import. This antibody, produced in rabbits, is highly specific for TOMM34 and has been validated for use in various applications, including Western blot and immunofluorescence.TOMM34 plays a crucial role in the transport of proteins into the mitochondria, essential for maintaining mitochondrial function and cell survival. Dysregulation of TOMM34 has been implicated in various diseases, including neurodegenerative disorders and cancer.
Understanding the role of TOMM34 in these conditions can provide insight into potential therapeutic targets.By utilizing the TOMM34 Polyclonal Antibody, researchers can effectively detect and study TOMM34 expression in a variety of cell types and tissues. This antibody enables detailed analysis of TOMM34 protein levels and localization, making it an indispensable tool for studies in mitochondrial biology and disease mechanisms.
Product Name:
[KO Validated] TOMM34 Rabbit Polyclonal Antibody
SKU:
CAB19960
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-309 of human TOMM34 (NP_006800.2).
The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats.
Purification Method:
Affinity purification
Gene ID:
10953
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and TOMM34 knockout (KO) HeLa cells, using [KO Validated] TOMM34 Rabbit pAb (CAB19960) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
