[KO Validated] TMPO Rabbit Polyclonal Antibody (CAB2534)
- SKU:
- CAB2534
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] TMPO Rabbit Polyclonal Antibody |
SKU: | CAB2534 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-410 of human TMPO (NP_001027454.1). |
Sequence: | MPEF LEDP SVLT KDKL KSEL VANN VTLP AGEQ RKDV YVQL YLQH LTAR NRPP LPAG TNSK GPPD FSSD EERE PTPV LGSG AAAA GRSR AAVG RKAT KKTD KPRQ EDKD DLDV TELT NEDL LDQL VKYG VNPG PIVG TTRK LYEK KLLK LREQ GTES RSST PLPT ISSS AENT RQNG SNDS DRYS DNEE DSKI ELKL EKRE PLKG RAKT PVTL KQRR VEHN QSYS QAGI TETE WTSG SSKG GPLQ ALTR ESTR GSRR TPRK RVET SEHF RIDG PVIS ESTP IAET IMAS SNES LVVN RVTG NFKH ASPI LPIT EFSD IPRR APKK PLTR AEVG EKTE ERRV ERDI LKEM FPYE ASTP TGIS ASCR RPIK GAAG RPLE LSDF RMEE SFSS KYVP KYVP LADV KSEK TKKG RS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TP; LAP2; CMD1T; LEMD4; PRO0868; TMPO |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus. |
Calculated MW: | 38kDa/50kDa/75kDa |
Observed MW: | 80kDa/51kDa |
Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription.
Purification Method: | Affinity purification |
Gene ID: | 7112 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |