The TFG Polyclonal Antibody (CAB19858) is a valuable tool for researchers studying the TFG protein, which plays a crucial role in cellular processes related to cancer and other diseases. Raised in rabbits, this antibody is highly specific and reactive with human samples, validated for use in Western blot applications. TFG, or TRK-fused gene, is involved in various cellular functions including cell growth, differentiation, and intracellular trafficking.
Dysregulation of TFG has been linked to tumorigenesis and cancer progression, making it a promising target for therapeutic interventions. With its ability to bind to the TFG protein, this antibody enables accurate detection and analysis in different cell types, making it ideal for studies in oncology and molecular biology. Understanding the role of TFG in disease processes is essential for developing targeted therapies and improving patient outcomes.
cytoplasm, cytosol, endoplasmic reticulum exit site
Calculated MW:
43kDa
Observed MW:
50kDa
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10342
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and TRK fused gene (TRK fused gene (TFG)) knockout (KO) HeLa cells, using [KO Validated] TRK fused gene (TFG) Rabbit pAb (CAB19858) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
