[KO Validated] SRI Rabbit Polyclonal Antibody (CAB19921)
The KO Validated SRI Polyclonal Antibody (CAB19921) is a powerful research tool designed for studying the SRI protein, which plays a crucial role in immune regulation. This rabbit-derived antibody is highly specific and reactive towards human samples, making it ideal for use in Western blot applications. By binding to the SRI protein, this antibody enables precise detection and analysis in a variety of cell types, making it a valuable asset for research in immunology and cancer biology.SRI, also known as stress response protein, is involved in regulating cellular stress responses and promoting cell survival in adverse conditions.
Its significance in immune function and stress adaptation makes it a promising target for studying diseases such as cancer, autoimmune disorders, and inflammatory conditions. By understanding the role of SRI in these contexts, researchers can identify new therapeutic strategies that leverage its functions to treat a range of diseases effectively.Overall, the KO Validated SRI Polyclonal Antibody (CAB19921) is a reliable tool for investigating the complex functions of the SRI protein, with implications for advancing our understanding of immune regulation and developing novel therapeutic interventions.
Product Name:
[KO Validated] SRI Rabbit Polyclonal Antibody
SKU:
CAB19921
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human SRI (NP_003121.1).
This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
Purification Method:
Affinity purification
Gene ID:
6717
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and SRI knockout (KO) HeLa cells, using [KO Validated] SRI Rabbit pAb (CAB19921) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.