[KO Validated] Src Rabbit Monoclonal Antibody (CAB19119)
- SKU:
- CAB19119
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] Src Rabbit Monoclonal Antibody |
SKU: | CAB19119 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Src (P12931). |
Sequence: | MGSN KSKP KDAS QRRR SLEP AENV HGAG GGAF PASQ TPSK PASA DGHR GPSA AFAP AAAE PKLF GGFN SSDT VTSP QRAG PLAG GVTT FVAL YDYE SRTE |
Tested Applications: | WB IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 400μg-600μg extracts of whole cells |
Synonyms: | ASV; SRC1; THC6; c-SRC; p60-Src; rc |
Positive Sample: | HeLa,Jurkat,Mouse brain,Mouse lung,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6714 |
Clone Number: | ARC0378 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |