The KO Validated SRC Rabbit Monoclonal Antibody (CAB19119) is a cutting-edge research tool designed for studying the SRC protein, a key player in cellular signaling pathways. This antibody, generated from rabbit monoclonal cells, boasts high specificity and sensitivity towards SRC, ensuring reliable results in experiments such as Western blotting and immunohistochemistry.SRC is a non-receptor tyrosine kinase that regulates various cellular processes, including cell growth, survival, and differentiation. Dysregulation of SRC has been implicated in numerous diseases, particularly cancer, making it a prime target for therapeutic interventions.
By utilizing the CAB19119 antibody, researchers can gain insights into the role of SRC in disease development and potentially identify novel treatment strategies.With its exceptional performance in detecting SRC protein in a variety of samples, the KO Validated SRC Rabbit Monoclonal Antibody (CAB19119) is a valuable asset for studies focused on understanding the molecular mechanisms underlying disease pathogenesis and exploring new avenues for targeted therapy.
Product Name:
[KO Validated] Src Rabbit Monoclonal Antibody
SKU:
CAB19119
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Src (P12931).
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6714
Clone Number:
ARC0378
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] Src Rabbit mAb (CAB19119) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
