[KO Validated] SMARCB1/SNF5 Rabbit Monoclonal Antibody (CAB3247)
- SKU:
- CAB3247
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| Product Name: | [KO Validated] SMARCB1/SNF5 Rabbit Monoclonal Antibody |
| SKU: | CAB3247 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMARCB1/SNF5 (NP_003064.2). |
| Sequence: | LWRR LATV EERK KIVA SSHG KKTK PNTK DHGY TTLA TSVT LLKA SEVE EILD GNDE KYKA VSIS TEPP TYLR EQKA KRNS QWVP TLPN SSHH LDAV PCST T |
| Tested Applications: | WB IHC-P ELISA |
| Recommended Dilution: | WB,1:1000 - 1:5000 IHC-P,1:50 - 1:200 |
| Synonyms: | RDT; CSS3; INI1; SNF5; Snr1; BAF47; INI-1; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; PPP1R144; F5 |
| Positive Sample: | 293F,K-562,NIH/3T3,Neuro-2a,Rat testis |
| Conjugate: | Unconjugated |
| Cellular Localization: | Nucleus |
| Calculated MW: | 44kDa |
| Observed MW: | 44kDa |
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 6598 |
| Clone Number: | ARC53139 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates, using SMARCB1/SNF5 Rabbit mAb (CAB3247) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:2000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s. |
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