The SLC25A23 Polyclonal Antibody (CAB19877) is a valuable tool for researchers studying the SLC25A23 protein, also known as mitochondrial calcium uptake 1 (MICU1). This antibody, generated in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.SLC25A23 is a key player in mitochondrial calcium transport, serving as a regulator of calcium homeostasis and impacting various cellular processes including metabolism, cell signaling, and apoptosis. Dysregulation of SLC25A23 has been linked to diseases such as neurodegenerative disorders, cancer, and metabolic diseases, making it a promising target for therapeutic research.
By using the SLC25A23 Polyclonal Antibody, researchers can effectively detect and analyze SLC25A23 protein levels in different cell types, providing insights into its function and role in disease pathogenesis. This antibody is a valuable tool for advancing our understanding of mitochondrial calcium transport and its implications in human health and disease.
Predicted to enable ATP transmembrane transporter activity. Involved in calcium import into the mitochondrion; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Located in mitochondrion.
Purification Method:
Affinity purification
Gene ID:
79085
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and SLC25A23 knockout (KO) 293T cells, using [KO Validated] SLC25A23 Rabbit pAb (CAB19877) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
