[KO Validated] SIRT3 Rabbit Polyclonal Antibody (CAB5718)
- SKU:
- CAB5718
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
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Description
Product Name: | [KO Validated] SIRT3 Rabbit Polyclonal Antibody |
SKU: | CAB5718 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 299-399 of human SIRT3 (NP_036371.1). |
Sequence: | PQRF LLHV VDFP MADL LLIL GTSL EVEP FASL TEAV RSSV PRLL INRD LVGP LAWH PRSR DVAQ LGDV VHGV ESLV ELLG WTEE MRDL VQRE TGKL DGPD K |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:20 - 1:50 IF/ICC,1:50 - 1:200 |
Synonyms: | SIR2L3; T3 |
Positive Sample: | HepG2,HeLa,293T,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion matrix. |
Calculated MW: | 44kDa |
Observed MW: | 28kDa |
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
Purification Method: | Affinity purification |
Gene ID: | 23410 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |