The KO Validated SELENBP1 Polyclonal Antibody (CAB1222) is a powerful tool for researchers studying SELENBP1, a protein involved in selenium metabolism and potential tumor suppression. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting SELENBP1 in human samples, making it suitable for Western blot applications.SELENBP1, also known as Selenium Binding Protein 1, has been implicated in various cellular processes, including antioxidant defense and cell differentiation. Its role in cancer biology has attracted significant interest, as it may act as a tumor suppressor or oncogene depending on the cellular context.
The KO Validated SELENBP1 Polyclonal Antibody enables precise detection and analysis of SELENBP1 expression in different cell types, facilitating research on the protein's function in cancer development and progression.By understanding the mechanisms underlying SELENBP1's functions, researchers can gain insights into how selenium metabolism influences cancer biology and potentially identify novel therapeutic targets for cancer treatment. The KO Validated SELENBP1 Polyclonal Antibody is a valuable tool for advancing our knowledge of SELENBP1 and its role in health and disease.
This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8991
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SELENBP1 antibody (CAB1222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
