The SCYL1 Polyclonal Antibody (CAB19913) is a powerful tool for researchers studying the SCYL1 protein, a key player in cellular processes such as vesicle trafficking and protein transport. This antibody is produced in rabbits and is highly specific for detecting SCYL1 in human samples, making it an ideal choice for applications such as Western blotting.SCYL1, also known as SCY1-like protein 1, is involved in regulating the Golgi structure and function, as well as mediating intracellular protein transport.
Its diverse roles in cellular processes make it a valuable target for research in cell biology and neurodegenerative diseases where protein trafficking is disrupted.By using the SCYL1 Polyclonal Antibody, researchers can gain deeper insights into the function and regulation of SCYL1, paving the way for advancements in understanding cellular mechanisms and potential therapeutic targets related to protein transport dysfunction.
Product Name:
[KO Validated] SCYL1 Rabbit Polyclonal Antibody
SKU:
CAB19913
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 460-740 of human SCYL1 (NP_065731.3).
This gene encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57410
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and SCYL1 knockout (KO) 293T cells, using [KO Validated] SCYL1 Rabbit pAb (CAB19913) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
