The S100A6 Polyclonal Antibody (CAB4104) is a valuable tool for researchers studying S100A6, a member of the S100 family of proteins involved in calcium-binding and regulating cellular processes. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to S100A6, this antibody enables the detection and analysis of S100A6 protein expression in various cell types.S100A6 is known to play a role in diverse cellular functions, including cell cycle progression, proliferation, differentiation, and apoptosis.
Dysregulation of S100A6 has been implicated in various diseases, making it a promising target for research in cancer, neurodegenerative disorders, and inflammatory conditions. Understanding the function of S100A6 is crucial for developing potential therapeutic interventions that target this protein's activity.Overall, the S100A6 Polyclonal Antibody (CAB4104) is a valuable tool for researchers interested in studying the role of S100A6 in cellular processes and diseases, enabling further insights into its potential implications for the development of novel treatments.
Product Name:
[KO Validated] S100A6 Rabbit Polyclonal Antibody
SKU:
CAB4104
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human S100A6 (NP_055439.1).
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
Purification Method:
Affinity purification
Gene ID:
6277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and S100A6 knockout (KO) HeLa cells, using [KO Validated] S100A6 Rabbit pAb (CAB4104) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
