[KO Validated] RhoC Rabbit Polyclonal Antibody (CAB1062)
- SKU:
- CAB1062
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] RhoC Rabbit Polyclonal Antibody |
SKU: | CAB1062 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RhoC (NP_786886.1). |
Sequence: | MAAI RKKL VIVG DGAC GKTC LLIV FSKD QFPE VYVP TVFE NYIA DIEV DGKQ VELA LWDT AGQE DYDR LRPL SYPD TDVI LMCF SIDS PDSL ENIP EKWT PEVK HFCP NVPI ILVG NKKD LRQD EHTR RELA KMKQ EPVR SEEG RDMA NRIS AFGY LECS AKTK EGVR EVFE MATR AGLQ VRKN KRRR GCPI L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | H9; ARH9; ARHC; RHOH9; oC |
Positive Sample: | 293T,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cleavage furrow, Cytoplasmic side, Lipid-anchor. |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 389 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |