The RCN2 Polyclonal Antibody (CAB19943) is a valuable tool for studying RCN2, a protein involved in calcium homeostasis and protein folding within the endoplasmic reticulum. This rabbit-derived antibody is highly specific for detecting RCN2 in human samples and has been validated for use in Western blot applications. By targeting the RCN2 protein, researchers can investigate its role in cellular processes related to protein quality control and calcium signaling.RCN2, also known as the reticulocalbin-2 protein, is essential for maintaining proper intracellular calcium levels and ensuring correct protein folding in the ER. Dysregulation of RCN2 has been linked to various diseases, including cancer and neurodegenerative disorders.
By using this antibody to study RCN2 expression and function, researchers can gain insights into the molecular mechanisms underlying these conditions and potentially identify new therapeutic targets.Overall, the RCN2 Polyclonal Antibody (CAB19943) offers a reliable and specific tool for researchers interested in exploring the role of RCN2 in cellular physiology and disease pathogenesis. Its versatility and high specificity make it an ideal choice for studies in fields such as cell biology, neuroscience, and cancer research.
Product Name:
[KO Validated] RCN2 Rabbit Polyclonal Antibody
SKU:
CAB19943
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-180 of human RCN2 (NP_002893.1).
The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5955
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and RCN2 knockout (KO) 293T cells, using [KO Validated] RCN2 Rabbit pAb (CAB19943) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
