The KO Validated RB Rabbit Monoclonal Antibody (CAB3618) is a cutting-edge tool for researchers studying CD300A, a key player in immune regulation. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for human samples, making it a reliable choice for Western blot applications. By targeting the CD300A protein, this antibody allows for precise detection and analysis across various cell types, making it an essential tool for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, is known for its role in modulating immune responses and maintaining immune balance. It has been implicated in regulating inflammation and suppressing allergic reactions, highlighting its importance in immune system function.
Researchers exploring diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions can benefit from studying CD300A to uncover potential therapeutic targets and mechanisms of disease progression.Overall, the KO Validated RB Rabbit Monoclonal Antibody (CAB3618) offers a reliable and precise tool for researchers delving into the complexities of CD300A and its impact on immune regulation. Its specificity and sensitivity make it an invaluable asset for advancing our understanding of immune function and exploring new avenues for therapeutic intervention.
Product Name:
[KO Validated] RB Rabbit Monoclonal Antibody
SKU:
CAB3618
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 729-928 of human RB (P06400).
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Purification Method:
Affinity purification
Gene ID:
5925
Clone Number:
ARC0810
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Confocal imaging of U-2 OS cells using RB Rabbit mAb (A3618,dilution 1:100)(Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012,dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
