The KO Validated Rab2A Polyclonal Antibody (CAB19982) is a valuable tool for research involving Rab2A, a small GTPase protein involved in regulating vesicular trafficking in cells. This rabbit polyclonal antibody is highly specific to Rab2A and has been validated for use in various experimental applications, including Western blot analysis.Rab2A is a key player in the intracellular transport of proteins and lipids, making it essential for maintaining cellular homeostasis and proper functioning. Dysregulation of Rab2A has been linked to various diseases, including neurodegenerative disorders and cancer, making it an important target for research in the fields of cell biology and disease pathology.
By using the KO Validated Rab2A Polyclonal Antibody (CAB19982), researchers can accurately detect and analyze Rab2A protein levels in different cell types and experimental conditions, providing valuable insights into its role in cellular processes and disease development. This antibody is a reliable tool for studying Rab2A function and may contribute to the development of potential therapies targeting Rab2A-related pathways.
Product Name:
[KO Validated] RAB2A Rabbit Polyclonal Antibody
SKU:
CAB19982
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human RAB2A (NP_002856.1).
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5862
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and RAB2A knockout (KO) 293T cells, using [KO Validated] RAB2A Rabbit pAb (CAB19982) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.