The KO-Validated Rab11a Polyclonal Antibody (CAB18048) is a valuable tool for researchers studying Rab11a, a key protein involved in intracellular trafficking and cell signaling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications.Rab11a is a member of the Rab GTPase family, known for its role in regulating endosomal recycling and membrane trafficking. It is involved in processes such as protein transport, cell migration, and cytokinesis, making it essential for normal cellular function. The Rab11a Polyclonal Antibody binds specifically to Rab11a protein, allowing for precise detection and analysis in a variety of cell types.
Research into Rab11a is valuable for understanding cellular processes such as vesicle transport, membrane recycling, and signaling pathways. Dysregulation of Rab11a has been implicated in various diseases, including cancer, neurological disorders, and infectious diseases. By studying the function and regulation of Rab11a, researchers can gain insights into disease mechanisms and potentially develop targeted therapies.Overall, the KO-Validated Rab11a Polyclonal Antibody is a reliable tool for investigating the role of Rab11a in cellular processes and disease pathology. Its specificity and sensitivity make it an ideal choice for immunology, cell biology, and cancer research studies.
Product Name:
[KO Validated] RAB11A Rabbit Polyclonal Antibody
SKU:
CAB18048
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human RAB11A (NP_004654.1).
The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8766
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and RAB11A knockout (KO) HeLa cells, using [KO Validated] RAB11A Rabbit pAb (CAB18048) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
