The Ko Validated PPP2R1B Polyclonal Antibody (CAB18089) is a valuable tool for researchers studying the PPP2R1B protein, a key regulatory subunit of protein phosphatase 2A (PP2A) involved in various cellular processes. This rabbit polyclonal antibody is highly specific and reacts with samples from various species, making it ideal for Western blot applications.PPP2R1B is known for its role in regulating cell growth, division, and apoptosis, making it a crucial player in cancer research and other disease studies.
By targeting and detecting PPP2R1B in different cell types, this antibody enables researchers to analyze its expression levels and activity, providing insights into its functions and potential therapeutic targets.With its high specificity and reliable performance, the Ko Validated PPP2R1B Polyclonal Antibody (CAB18089) is a valuable tool for researchers interested in exploring the intricate mechanisms of PPP2R1B and its implications in various cellular processes and diseases.
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
5519
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and PP2A-Abeta/PR65β/PP2A-Aβ/PR65β/PPP2R1B knockout (KO) 293T cells, using [KO Validated] PP2A-Aβ/PR65β/PPP2R1B Rabbit pAb (CAB18089) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
