The KO Validated PPP1CC Polyclonal Antibody (CAB4035) is a valuable tool for researchers studying PPP1CC, a key enzyme involved in cell cycle regulation and cellular signaling pathways. This antibody, derived from rabbit polyclonal sources, is highly specific and sensitive for detecting PPP1CC in various sample types, including human tissues.PPP1CC is a critical protein phosphatase that plays a vital role in regulating cell division, proliferation, and apoptosis. Dysregulation of PPP1CC has been linked to various diseases, including cancer and neurodegenerative disorders. By targeting PPP1CC with this validated antibody, researchers can gain valuable insights into the function and signaling pathways associated with this enzyme.
The use of the KO Validated PPP1CC Polyclonal Antibody (CAB4035) in Western blot applications provides researchers with a powerful tool for analyzing PPP1CC expression levels and activity in different cell types and experimental conditions. This antibody's high specificity and sensitivity make it an ideal choice for studies focusing on cell cycle regulation, signaling pathways, and disease mechanisms related to PPP1CC.
Product Name:
[KO Validated] PPP1CC Rabbit Polyclonal Antibody
SKU:
CAB4035
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human PPP1CC (NP_002701.1).
The protein encoded by this gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. This gene encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5501
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PPP1CC antibody (CAB4035) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
