[KO Validated] PNP Rabbit Polyclonal Antibody (CAB19885)
- SKU:
- CAB19885
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] PNP Rabbit Polyclonal Antibody |
SKU: | CAB19885 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human PNP (NP_000261.2). |
Sequence: | MENG YTYE DYKN TAEW LLSH TKHR PQVA IICG SGLG GLTD KLTQ AQIF DYGE IPNF PRST VPGH AGRL VFGF LNGR ACVM MQGR FHMY EGYP LWKV TFPV RVFH LLGV DTLV VTNA AGGL NPKF EVGD IMLI RDHI NLPG FSGQ NPLR GPND ERFG DRFP AMSD AYDR TMRQ RALS TWKQ MGEQ RELQ EGTY VMVA GPSF ETVA ECRV LQKL GADA VGMS TVPE VIVA RHCG LRVF GFSL ITNK VIMD YESL EKAN HEEV LAAG KQAA QKLE QFVS ILMA SIPL PDKA S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | NP; PUNP; PRO1837 |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cytoskeleton. |
Calculated MW: | 32kDa |
Observed MW: | 30kDa |
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
Purification Method: | Affinity purification |
Gene ID: | 4860 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |