The Peroxiredoxin-2 Polyclonal Antibody (CAB1919) is a valuable tool for research involving Peroxiredoxin-2, a vital enzyme involved in antioxidant defense and cell protection. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for Western blot applications. Specifically targeting Peroxiredoxin-2, this antibody allows for the detection and analysis of this important protein in a variety of cell types.Peroxiredoxin-2 is known for its crucial role in protecting cells from oxidative stress and maintaining redox balance. Its involvement in various cellular processes, including cell growth and differentiation, highlights its significance in health and disease.
Research on Peroxiredoxin-2 is particularly relevant in cancer studies, as dysregulation of this enzyme has been linked to tumor development and progression.By using the Peroxiredoxin-2 Polyclonal Antibody, researchers can enhance their understanding of the mechanisms underlying oxidative stress and its impact on cellular function. This antibody is a valuable tool for investigating Peroxiredoxin-2 in the context of cancer, aging, and other oxidative stress-related disorders, ultimately leading to potential therapeutic interventions targeting this enzyme.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Purification Method:
Affinity purification
Gene ID:
7001
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts from normal (control) and Peroxiredoxin 2 (Peroxiredoxin 2 (PRDX2)) knockout (KO) 293T cells, using Peroxiredoxin 2 (Peroxiredoxin 2 (PRDX2)) antibody (CAB1919) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
