[KO Validated] Peroxiredoxin 2 (PRDX2) Rabbit Polyclonal Antibody (CAB1919)
- SKU:
- CAB1919
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] Peroxiredoxin 2 (PRDX2) Rabbit Polyclonal Antibody |
SKU: | CAB1919 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Peroxiredoxin 2 (Peroxiredoxin 2 (PRDX2)) (NP_859428.1). |
Sequence: | MASG NARI GKPA PDFK ATAV VDGA FKEV KLSD YKGK YVVL FFYP LDFT FVCP TEII AFSN RAED FRKL GCEV LGVS VDSQ FTHL AWYE QGPK REVA AKLT PSGP SSVA SWPL LNLW NLRF PIVK IMET LPPK SLRM MTVI SI |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a; 2) |
Positive Sample: | HepG2,Mouse brain,Rat brain,Rat spleen,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm. |
Calculated MW: | 22kDa |
Observed MW: | 22kDa |
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Purification Method: | Affinity purification |
Gene ID: | 7001 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |