[KO Validated] PDCD10 Rabbit Polyclonal Antibody (CAB15400)
- SKU:
- CAB15400
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | [KO Validated] PDCD10 Rabbit Polyclonal Antibody |
SKU: | CAB15400 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PDCD10 (NP_009148.2). |
Sequence: | MRMT MEEM KNEA ETTS MVSM PLYA VMYP VFNE LERV NLSA AQTL RAAF IKAE KENP GLTQ DIIM KILE KKSV EVNF TESL LRMA ADDV EEYM IERP EPEF QDLN EKAR ALKQ ILSK IPDE INDR VRFL QTIK DIAS AIKE LLDT VNNV FKKY QYQN RRAL EHQK KEFV KYSK SFSD TLKT YFKD GKAI NVFV SANR LIHQ TNLI LQTF KTVA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | CCM3; TFAR15; 10 |
Positive Sample: | A-431,K-562,U-251MG,SKOV3,Mouse brain,Mouse kidney,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic side, Golgi apparatus membrane, Peripheral membrane protein. |
Calculated MW: | 25kDa |
Observed MW: | 26kDa |
This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Purification Method: | Affinity purification |
Gene ID: | 11235 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |