[KO Validated] PAK2 Rabbit Polyclonal Antibody (CAB18093)
- SKU:
- CAB18093
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | [KO Validated] PAK2 Rabbit Polyclonal Antibody |
SKU: | CAB18093 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-212 of human PAK2 (NP_000903.2). |
Sequence: | MDSP IQIF RGEP GPTC APSA CLPP NSSA WFPG WAEP DSNG SAGS EDAQ LEPA HISP AIPV IITA VYSV VFVV GLVG NSLV MFVI IRYT KMKT ATNI YIFN LALA DALV TTTM PFQS TVYL MNSW PFGD VLCK IVIS IDYY NMFT SIFT LTMM SVDR YIAV CHPV KALD FRTP LKAK IINI CIWL LSSS VGIS AIVL GGTK VRED VDVI ECSL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | KNO2; PAK65; PAKgamma; K2 |
Positive Sample: | HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasm, Lipid-anchor, Membrane, Nucleus, perinuclear region. |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.
Purification Method: | Affinity purification |
Gene ID: | 5062 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |