[KO Validated] OCRL Rabbit Polyclonal Antibody (CAB19976)
- SKU:
- CAB19976
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] OCRL Rabbit Polyclonal Antibody |
SKU: | CAB19976 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human OCRL (NP_001578.2). |
Sequence: | MEPP LPVG AQPL ATVE GMEM KGPL REPC ALTL AQRN GQYE LIIQ LHEK EQHV QDII PINS HFRC VQEA EETL LIDI ASNS GCKI RVQG DWIR ERRF EIPD EEHC LKFL SAVL AAQK AQSQ LLVP EQKD SSSW YQKL DTKD KPSV FSGL LGFE DNFS SMNL DKKI NSQN QPTG IHRE PPPP PFSV NKML PREK EASN KEQP KVTN TMRK LFVP NTQS GQRE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LOCR; DENT2; NPHL2; OCRL1; Dent-2; INPP5F; OCRL-1; RL |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasmic vesicle, Early endosome membrane, Endosome, Golgi apparatus, Membrane, cilium, clathrin-coated pit, phagosome membrane, photoreceptor outer segment, trans-Golgi network. |
Calculated MW: | 104kDa |
Observed MW: | 104kDa |
This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 4952 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |