The NRD1 Rabbit Polyclonal Antibody (CAB19857) is a reliable tool for researchers studying NRD1, a key player in RNA metabolism and regulation. This antibody, raised in rabbits, has been rigorously validated for use in various applications, including immunofluorescence and immunohistochemistry. It specifically binds to the NRD1 protein, allowing for precise detection and analysis in a variety of cell types.NRD1 is known to be involved in RNA degradation and transcription termination, making it an essential component in gene expression regulation. Its dysregulation has been linked to various diseases, including cancer and neurological disorders.
By studying the function and localization of NRD1 using this antibody, researchers can gain valuable insights into the molecular mechanisms underlying these conditions and potentially identify novel therapeutic targets. Overall, the NRD1 Rabbit Polyclonal Antibody (CAB19857) is a versatile tool that can significantly advance research in the fields of molecular biology, genetics, and pathology. Its high specificity and sensitivity make it a valuable asset for any scientist exploring the complex role of NRD1 in RNA biology and disease pathogenesis.
Product Name:
[KO Validated] NRD1 Rabbit Polyclonal Antibody
SKU:
CAB19857
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-400 of human NRD1 (NP_001095132.1).
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4898
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and NRD1 knockout (KO) 293T cells, using [KO Validated] NRD1 Rabbit pAb (CAB19857) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
