The NNMT Polyclonal Antibody (CAB18033) is a powerful tool for researchers studying the enzyme Nicotinamide N-methyltransferase (NNMT), which plays a role in various physiological processes such as metabolism, inflammation, and immune response regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples, making it an excellent choice for Western blotting and other applications. By targeting the NNMT protein, this antibody allows for the detection and analysis of NNMT expression in different cell types, making it an invaluable resource for studies in metabolic disorders, cancer research, and immune system function.
NNMT is known to be involved in the methylation of nicotinamide, a process that has been implicated in various diseases including cancer, metabolic disorders, and inflammation. The ability to accurately measure NNMT levels in cells and tissues is essential for understanding its role in these conditions and for developing targeted therapies. By using the NNMT Polyclonal Antibody, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets.
Product Name:
[KO Validated] NNMT Rabbit Polyclonal Antibody
SKU:
CAB18033
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human NNMT (NP_006160.1).
N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Purification Method:
Affinity purification
Gene ID:
4837
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from A-549 cells, using NNMT Rabbit pAb (CAB18033) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
