The NDUFV2 Polyclonal Antibody (CAB19936) is a valuable tool for research involving NDUFV2, a subunit of the NADH:ubiquinone oxidoreductase enzyme complex responsible for energy production in the mitochondria. This rabbit polyclonal antibody is highly specific to human samples and has been validated for use in Western blot applications. It specifically binds to the NDUFV2 protein, allowing for precise detection and analysis in various cell types.NDUFV2 is essential for the function of the mitochondrial respiratory chain, playing a crucial role in cellular energy metabolism. Dysregulation of NDUFV2 has been implicated in various diseases, including metabolic disorders, neurodegenerative diseases, and cancer.
Research into NDUFV2 can provide insights into these conditions and potential targets for therapeutic interventions.This NDUFV2 Polyclonal Antibody is a reliable tool for studying the function and regulation of NDUFV2, making it ideal for researchers in the fields of biochemistry, cell biology, and mitochondrial research. Its high specificity and sensitivity ensure accurate and reproducible results, contributing to a deeper understanding of mitochondrial function and associated diseases.
Product Name:
[KO Validated] NDUFV2 Rabbit Polyclonal Antibody
SKU:
CAB19936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human NDUFV2 (NP_066552.2).
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19.
Purification Method:
Affinity purification
Gene ID:
4729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and NDUFV2 knockout (KO) HeLa cells, using [KO Validated] NDUFV2 Rabbit pAb (CAB19936) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
