[KO Validated] NDUFS2 Rabbit Polyclonal Antibody (CAB12858)
- SKU:
- CAB12858
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] NDUFS2 Rabbit Polyclonal Antibody |
SKU: | CAB12858 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 204-463 of human NDUFS2 (NP_004541.1). |
Sequence: | FEER EKMF EFYE RVSG ARMH AAYI RPGG VHQD LPLG LMDD IYQF SKNF SLRL DELE ELLT NNRI WRNR TIDI GVVT AEEA LNYG FSGV MLRG SGIQ WDLR KTQP YDVY DQVE FDVP VGSR GDCY DRYL CRVE EMRQ SLRI IAQC LNKM PPGE IKVD DAKV SPPK RAEM KTSM ESLI HHFK LYTE GYQV PPGA TYTA IEAP KGEF GVYL VSDG SSRP YRCK IKAP GFAH LAGL DKMS KGHM LADV VAII GTQD IVFG EVDR |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | CI-49; MC1DN6; S2 |
Positive Sample: | LO2,HeLa,293T,Mouse brain,Mouse kidney,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein. |
Calculated MW: | 53kDa |
Observed MW: | 49kDa |
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4720 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |