The NDUFC2 Polyclonal Antibody (CAB15073) is a valuable tool for research focusing on NDUFC2, a critical subunit of mitochondrial complex I involved in oxidative phosphorylation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to the NDUFC2 protein, this antibody enables accurate detection and analysis in a variety of cell types, facilitating studies in mitochondrial function and energy metabolism.NDUFC2 is essential for the functionality of mitochondrial complex I, the first and largest enzyme complex in the electron transport chain.
Mutations in NDUFC2 have been linked to a variety of mitochondrial diseases, highlighting its importance in cellular energy production. Research on NDUFC2 is crucial for advancing our understanding of these conditions and developing potential therapies to target mitochondrial dysfunction.Overall, the NDUFC2 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of NDUFC2 in mitochondrial function and its implications for various diseases. Its high specificity and sensitivity make it a reliable choice for studying the complex mechanisms of oxidative phosphorylation and energy production in cells.
Product Name:
[KO Validated] NDUFC2 Rabbit Polyclonal Antibody
SKU:
CAB15073
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NDUFC2 (NP_004540.1).
Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Part of mitochondrial respiratory chain complex I. Implicated in nuclear type mitochondrial complex I deficiency.
Purification Method:
Affinity purification
Gene ID:
4718
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] NDUFC2 Rabbit pAb (CAB15073) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
