The NDUFA7 Polyclonal Antibody (CAB8441) is a valuable tool for researchers studying NDUFA7, a subunit of the mitochondrial respiratory chain complex I involved in energy production. This antibody is derived from rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding specifically to the NDUFA7 protein, researchers can easily detect and analyze its expression in various cell types, providing insight into mitochondrial function and cellular metabolism.
NDUFA7 is essential for electron transfer within complex I of the respiratory chain, contributing to the generation of ATP through oxidative phosphorylation. Dysregulation of this process has been implicated in various diseases, including metabolic disorders, neurodegenerative conditions, and cancer. By studying the role of NDUFA7, researchers can gain a better understanding of mitochondrial dysfunction and potentially identify new therapeutic targets for these diseases.
Product Name:
[KO Validated] NDUFA7 Rabbit Polyclonal Antibody
SKU:
CAB8441
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human NDUFA7 (NP_004992.2).
Sequence:
MASA TRLI QRLR NWAS GHDL QGKL QLRY QEIS KRTQ PPPK LPVG PSHK LSNN YYCT RDGR RESV PPSI IMSS QKAL VSGK PAES SAVA ATEK KAVT PAPP IKRW ELSS DQPY L
This gene encodes a subunit of NADH:ubiquinone oxidoreductase (complex I), which is a multiprotein complex located in the inner mitochondrial membrane. Complex I functions in the transfer of electrons from NADH to the respiratory chain.
Purification Method:
Affinity purification
Gene ID:
4701
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NDUFA7 antibody (CAB8441) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
