The MPP2 Polyclonal Antibody (CAB19909) is a valuable tool for researchers studying the MPP2 protein, a key player in cell signaling pathways and neuronal development. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in various applications, including Western blotting. By specifically binding to the MPP2 protein, researchers can easily detect and analyze its presence in different cell types, making it ideal for investigations in neuroscience and developmental biology.MPP2, also known as membrane protein, palmitoylated 2, is involved in cellular processes such as synaptic plasticity and neuronal migration, highlighting its importance in brain development and function.
Studies have shown that dysregulation of MPP2 expression can lead to neurological disorders and cognitive impairment, making it a promising target for research in neurobiology and neurodegenerative diseases. By understanding the function of MPP2, researchers can gain insights into the mechanisms underlying brain disorders and potentially develop targeted therapies to address them.
Product Name:
[KO Validated] MPP2 Rabbit Polyclonal Antibody
SKU:
CAB19909
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MPP2 (NP_005365.3).
Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction.
Purification Method:
Affinity purification
Gene ID:
4355
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and MPP2 knockout (KO) 293T cells, using [KO Validated] MPP2 Rabbit pAb (CAB19909) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10S.
