The KO validated MAPK6 Polyclonal Antibody (CAB15304) is a crucial tool for researchers studying the MAPK6 protein, a member of the mitogen-activated protein kinase (MAPK) family involved in various cellular processes including cell growth, differentiation, and survival. This antibody, produced in rabbits, has been rigorously tested and validated for use in Western blot applications with a high specificity for human samples.MAPK6 is known to play a key role in the regulation of cell proliferation and differentiation, making it a significant target for studies in cancer biology, developmental biology, and signal transduction pathways.
The MAPK6 Polyclonal Antibody binds specifically to the MAPK6 protein, allowing for precise detection and analysis in a variety of cell types and experimental conditions.The reliable performance and accuracy of the MAPK6 Polyclonal Antibody make it an indispensable tool for researchers investigating the functions and mechanisms of MAPK6 in health and disease. Its versatility and specificity make it an ideal choice for studies aiming to elucidate the intricate signaling pathways involving MAPK6 and its potential implications for therapeutic interventions in conditions such as cancer and neurological disorders.
Product Name:
[KO Validated] MAPK6 Rabbit Polyclonal Antibody
SKU:
CAB15304
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 372-721 of human MAPK6 (NP_002739.1).
The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.
Purification Method:
Affinity purification
Gene ID:
5597
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAPK6 Rabbit pAb (CAB15304) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
