The LYAR Polyclonal Antibody (CAB19900) is a valuable tool for researchers studying LYAR, a protein that plays a key role in gene regulation and cell proliferation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the LYAR protein, this antibody enables precise detection and analysis in a variety of cell types, making it an essential reagent for studies focused on understanding gene expression and cell growth mechanisms.LYAR, also known as cell growth-regulating nucleolar protein, is essential for maintaining the balance between cell proliferation and differentiation.
Dysregulation of LYAR expression has been linked to a variety of diseases, including cancer and developmental disorders. By investigating the function of LYAR, researchers can gain insights into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.Overall, the LYAR Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of LYAR in cellular processes and disease development. Its specificity and reliability make it an essential component of any study involving gene regulation and cell proliferation.
Product Name:
[KO Validated] LYAR Rabbit Polyclonal Antibody
SKU:
CAB19900
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 10-160 of human LYAR (NP_060286.1).
Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
55646
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and LYAR knockout (KO) 293T cells, using [KO Validated] LYAR Rabbit pAb (CAB19900) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
