The LTA4H Polyclonal Antibody (CAB19939) is a valuable tool for researchers studying LTA4H, an enzyme involved in the biosynthesis of leukotriene B4, a potent lipid mediator. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it an ideal choice for Western blot applications.LTA4H is a key enzyme in the inflammatory pathway, playing a crucial role in the immune response and inflammatory processes. By targeting LTA4H, researchers can gain insights into the mechanisms underlying inflammatory diseases and potentially develop novel therapeutic strategies.
With its high specificity and reactivity, the LTA4H Polyclonal Antibody is a reliable tool for researchers studying inflammation, immune response, and related diseases. Its validation for use in Western blot applications ensures accurate and reliable results, making it a valuable resource for studies in immunology and drug discovery.
Product Name:
[KO Validated] LTA4H Rabbit Polyclonal Antibody
SKU:
CAB19939
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 312-611 of human LTA4H (NP_000886.1).
The protein encoded by this gene is an enzyme that contains both hydrolase and aminopeptidase activities. The hydrolase activity is used in the final step of the biosynthesis of leukotriene B4, a proinflammatory mediator. The aminopeptidase activity has been shown to degrade proline-glycine-proline (PGP), a neutrophil chemoattractant and biomarker for chronic obstructive pulmonary disease (COPD). Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and LTA4H knockout (KO) 293T cells, using [KO Validated] LTA4H Rabbit pAb (CAB19939) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
