[KO Validated] IRF3 Rabbit Monoclonal Antibody (CAB19717)
- SKU:
- CAB19717
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | [KO Validated] IRF3 Rabbit Monoclonal Antibody |
SKU: | CAB19717 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human IRF3 (Q14653). |
Sequence: | DFGI FQAW AEAT GAYV PGRD KPDL PTWK RNFR SALN RKEG LRLA EDRS KDPH DPHK IYEF VNSG VGDF SQPD TSPD TNGG GSTS DTQE DILD ELLG NMVL A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | IIAE7; F3 |
Positive Sample: | Jurkat,293T,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 57kDa |
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.
Purification Method: | Affinity purification |
Gene ID: | 3661 |
Clone Number: | ARC0198 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |