The IPO4 Polyclonal Antibody (CAB19902) is a valuable tool for researchers studying IPO4, a key protein involved in nuclear transport processes. This antibody, developed in rabbits, shows high reactivity with human samples and has been validated for use in Western blotting applications. By specifically binding to the IPO4 protein, this antibody enables the detection and analysis of IPO4 in various cell types, making it ideal for studies in cell biology and molecular biology.IPO4, also known as Importin-4, plays a crucial role in the transportation of proteins into the nucleus, facilitating essential cellular functions such as gene expression and signaling.
Understanding the mechanisms by which IPO4 operates can provide valuable insights into various cellular processes and has implications for the development of therapeutic strategies targeting nuclear transport pathways. Research involving IPO4 may contribute to advances in fields such as cancer biology, developmental biology, and neurobiology.
Product Name:
[KO Validated] IPO4 Rabbit Polyclonal Antibody
SKU:
CAB19902
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 728-1081 of human IPO4 (NP_078934.3).
Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in DNA replication-dependent chromatin assembly; DNA replication-independent chromatin assembly; and protein import into nucleus. Located in chromatin. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
79711
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and IPO4 knockout (KO) 293T cells, using [KO Validated] IPO4 Rabbit pAb (CAB19902) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
