The Integrin Alpha 2 Polyclonal Antibody (CAB7629) is an essential tool for researchers studying integrin alpha 2, a cell adhesion molecule involved in cell signaling and cell adhesion processes. This antibody, developed using rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Integrin alpha 2 plays a crucial role in cell-matrix interactions, controlling cell migration, proliferation, and differentiation. Its involvement in various biological processes such as wound healing, angiogenesis, and tumor progression makes it a key target for investigation in the fields of cancer research and vascular biology.
By utilizing the integrin alpha 2 Polyclonal Antibody, researchers can detect and analyze the expression levels of integrin alpha 2 in different cell types, providing valuable insights into its functions and potential therapeutic applications. This antibody is a valuable asset for studies aiming to understand the molecular mechanisms underlying cell adhesion and migration, paving the way for the development of targeted therapies for various diseases.
This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
3673
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KO Validated] Integrin alpha 2 (ITGA2/CD49b) Rabbit pAb (CAB7629) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
