[KO Validated] IKKγ Rabbit Polyclonal Antibody (CAB12536)
- SKU:
- CAB12536
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | [KO Validated] IKKγ Rabbit Polyclonal Antibody |
SKU: | CAB12536 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-419 of human IKKγ (NP_003630.1). |
Sequence: | MNRH LWKS QLCE MVQP SGGP AADQ DVLG EESP LGKP AMLH LPSE QGAP ETLQ RCLE ENQE LRDA IRQS NQIL RERC EELL HFQA SQRE EKEF LMCK FQEA RKLV ERLG LEKL DLKR QKEQ ALRE VEHL KRCQ QQMA EDKA SVKA QVTS LLGE LQES QSRL EAAT KECQ ALEG RARA ASEQ ARQL ESER EALQ QQHS VQVD QLRM QGQS VEAA LRME RQAA SEEK RKLA QLQV AYHQ LFQE YDNH IKSS VVGS ERKR GMQL EDLK QQLQ QAEE ALVA KQEV IDKL KEEA EQHK IVME TVPV LKAQ ADIY KADF QAER QARE KLAE KKEL LQEQ LEQL QREY SKLK ASCQ ESAR IEDM RKRH VEVS QAPL PPAP AYLS SPLA LPSQ RRSP PEEP PDFC CPKC QYQA PDMD TLQI HVME CIE |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | IP; IP1; IP2; FIP3; IKKG; IPD2; NEMO; FIP-3; Fip3p; IMD33; SAIDX; AMCBX1; EDAID1; IKKAP1; ZC2HC9; IKK-gamma; Kγ |
Positive Sample: | A-549,Mouse liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 48kDa |
Observed MW: | 48kDa |
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Purification Method: | Affinity purification |
Gene ID: | 8517 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |