[KO Validated] HuR/ELAVL1 Rabbit Monoclonal Antibody (CAB19622)
- SKU:
- CAB19622
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | [KO Validated] HuR/ELAVL1 Rabbit Monoclonal Antibody |
SKU: | CAB19622 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HuR/ELAVL1 (Q15717). |
Sequence: | MSNG YEDH MAED CRGD IGRT NLIV NYLP QNMT QDEL RSLF SSIG EVES AKLI RDKV AGHS LGYG FVNY VTAK DAER AINT LNGL RLQS KTIK VSYA RPSS |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HUR; Hua; MelG; ELAV1; L1 |
Positive Sample: | 293T,HeLa,Jurkat,Mouse brain,Mouse spleen,Mouse thymus,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 36kDa |
Observed MW: | 36kDa |
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Purification Method: | Affinity purification |
Gene ID: | 1994 |
Clone Number: | ARC0101 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |