The Hsp90 Beta Polyclonal Antibody (CAB18015) is a valuable tool for researchers studying the heat shock protein 90 beta (Hsp90β), a chaperone protein involved in cellular stress response and protein folding. This antibody, derived from rabbits, shows high reactivity with human samples and has been validated for use in Western blotting applications.Hsp90β is a key player in maintaining cellular homeostasis and promoting cell survival under stressful conditions. Its role in protein folding and stability makes it an attractive target for studies in cancer research and molecular biology. By detecting and analyzing Hsp90β levels in different cell types, researchers can gain insights into its function and potential therapeutic implications.
Understanding the mechanisms of Hsp90β activity is essential for developing targeted therapies for cancer and other diseases where protein misfolding and cellular stress are prominent features. The Hsp90 Beta Polyclonal Antibody provides a reliable tool for investigating the role of this important chaperone protein in various cellular processes, advancing our knowledge of cellular stress response and potential therapeutic strategies.
Product Name:
[KO Validated] Hsp90β Rabbit Polyclonal Antibody
SKU:
CAB18015
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Monkey
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Hsp90β (NP_031381.2).
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
Purification Method:
Affinity purification
Gene ID:
3326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and HSP90AB1 knockout (KO) HeLa cells, using [KO Validated] Hsp90β Rabbit pAb (CAB18015) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
