The HNRNPR Polyclonal Antibody (CAB19999) is a research tool designed for the study of heterogeneous nuclear ribonucleoprotein R (HNRNPR), a protein involved in various aspects of RNA metabolism. This rabbit polyclonal antibody has been validated for use in Western blot applications and is highly reactive with human samples.HNRNPR plays a critical role in pre-mRNA processing, mRNA splicing, and mRNA stability, making it a key player in gene expression regulation. Dysregulation of HNRNPR has been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting its importance in molecular biology research.
By targeting the HNRNPR protein, this antibody enables the detection and analysis of HNRNPR expression in different cell types, providing valuable insights into its function and potential therapeutic relevance. Researchers in molecular biology, genetics, and biomedical sciences can utilize this antibody to further their understanding of RNA biology and its implications in disease pathology.
Product Name:
[KO Validated] HNRNPR Rabbit Polyclonal Antibody
SKU:
CAB19999
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-633 of human HNRNPR (NP_005817.1).
This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10.
Purification Method:
Affinity purification
Gene ID:
10236
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and HNRNPR knockout (KO) 293T cells, using [KO Validated] HNRNPR Rabbit pAb (CAB19999) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
