The HMG20B Polyclonal Antibody (CAB19951) is a valuable tool for research involving HMG20B, a protein involved in chromatin remodeling and gene regulation. This antibody, produced in rabbits, has been validated for its reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the HMG20B protein, this antibody enables researchers to detect and analyze HMG20B expression in various cell types, making it an ideal choice for studies in molecular biology and epigenetics.HMG20B, also known as high mobility group protein 20B, plays a crucial role in modulating gene expression by influencing chromatin structure and organization.
Its involvement in epigenetic regulation makes it a promising target for research in fields such as cancer biology, developmental biology, and stem cell research. Understanding the function of HMG20B can provide valuable insights into the mechanisms governing gene expression and cellular differentiation, shedding light on potential therapeutic interventions for a variety of diseases.
Product Name:
[KO Validated] HMG20B Rabbit Polyclonal Antibody
SKU:
CAB19951
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-317 of human HMG20B (NP_006330.2).
Predicted to enable DNA binding activity. Predicted to be involved in regulation of gene expression. Predicted to act upstream of or within negative regulation of protein sumoylation; positive regulation of neuron differentiation; and skeletal muscle cell differentiation. Located in nuclear body.
Purification Method:
Affinity purification
Gene ID:
10362
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and HMG20B knockout (KO) 293T cells, using [KO Validated] HMG20B Rabbit pAb (CAB19951) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
