The KO Validated HINT1 Polyclonal Antibody (CAB10221) is a valuable tool for researchers studying the HINT1 protein, which is involved in various cellular processes including protein-protein interactions and nucleic acid binding. This polyclonal antibody, produced in rabbits, has been rigorously tested for validation in knockout (KO) models, ensuring reliable and specific detection of HINT1 in experimental settings.With its high reactivity towards human samples, the CAB10221 antibody is ideally suited for use in Western blotting applications, allowing for the precise identification and quantification of HINT1 protein levels in different cell types and tissues.
Its specificity for HINT1 makes it a valuable tool for investigating the role of this protein in cellular signaling pathways, gene regulation, and disease development.The HINT1 protein has been implicated in various health conditions, including neurodegenerative disorders, cancer, and drug addiction, highlighting its importance in cellular physiology and disease progression. By utilizing the CAB10221 antibody in their research, scientists can gain valuable insights into the function and regulation of HINT1, paving the way for the development of novel therapeutic strategies targeting this protein in the future.
Product Name:
[KO Validated] HINT1 Rabbit Polyclonal Antibody
SKU:
CAB10221
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-126 of human HINT1 (NP_005331.1).
This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed.
Purification Method:
Affinity purification
Gene ID:
3094
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HINT1 antibody (CAB10221) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
